ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
|Principal Investigator's Name:||Joshua Shulman|
|Institution:||Brigham and Women's Hospital|
|Proposed Analysis:||I am conducting genome-wide association studies for intermediate cognitive and neuropathological phenotypes in order discover new Alzheimer's Disease susceptibility loci. This work is being performed with Dr. Philip De Jager (Brigham and Women's Hospital) and in collaboration with Dr. David Bennett (Rush University), and leverages the resources of the Religious Orders Study and Rush Memory and Aging Project, two prospective cohorts for the study of cognitive aging and Alzheimer's Disease. I propose to use the ADNI clinical biomarker data (including CSF amyloid-beta and Tau) as well as the imaging data (including MRI and PIB scans), along with genome-wide genotyping data, as a replication cohort for loci identified in my discovery genome-wide association study for Alzheimer's neuropathology and cognitive decline.|