ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
|Principal Investigator's Name:||Clement Loy|
|Institution:||The University of Sydney|
|Department:||School of Public Health|
|Proposed Analysis:||We are performing a systematic review of all studies assessing the diagnostic accuracy of CSF biomarkers (aBeta42, aBeta40, Tau, Phospho-Tau, Tau/ABeta ratios) in the diagnosis of Alzheimer Disease, using the normal population or MCI population as controls. Individual level data from ADNI will allow us to avoid 'double counting' different studies already published from ADNI with test accuracy data. It will also allow us to carry out finer-grain analyses including exploration of the effect of threshold shift.|