ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
|Principal Investigator's Name:||Jeremy Cohen|
|Institution:||Xavier University of Louisiana|
|Proposed Analysis:||I spent the past several years developing a novel real-space morphometric technique for measuring human insular cortex. My method aims to segment the insula into functionally relevant anterior-posterior parts, as opposed to using gross anatomical segmentation. I published 2 studies using this method with a third currently in submission. Insular cortex has been shown to be an age sensitive region previously (using indirect methods), and has also been shown to express high concentrations of plaques and tangles in AD. I plan to use my ADNI access to examine insular volume differences in CN, MCI, and AD. I also plan to correlate changes in insular volumes to levels of Amyloid Beta, Tau and specific cognitive measures.|