ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
|Principal Investigator's Name:||Ekaterina Tchistiakova|
|Institution:||University of Toronto|
|Proposed Analysis:||In the following study we will use structural Magnetic Resonance Imaging (MRI) scans to examine the effect of diabetes and hypertension on the brain structure. The voxel-wise structural analysis will be performed to identify the brain regions that exhibit the highest degree of atrophy and are therefore most affected by these conditions. In addition to the structural changes we’re also interested in exploring the perfusion differences in these population by examining the Arterial Spin Labeling (ASL) MRI scans. Finally, we will explore the correlation between the structural atrophy and perfusion changes caused by two conditions.|