ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
|Principal Investigator's Name:||George Kagadis|
|Institution:||University of Patras|
|Proposed Analysis:||We are currently working on a project funded by the European Social Fund entitled ‘Mining Biomedical Data and Images: Development of Algorithms and Applications (BIOMEDMINE)’ which is focused on the development of innovative algorithms for knowledge extraction from biological and medical data. It is aiming at the discovery of new rules that govern the operation of the nervous system on specific illnesses. Specifically we aim at the understanding of development mechanisms of various neurodegenerative diseases, such as multiple sclerosis, Alzheimer’s and Parkinson’s disease and the discovery of potential markers for diagnosis, prognosis and treatment of various diseases and disorders of the nervous system. The proposed analysis will include the development of a methodological framework for image and data mining which includes algorithms for feature extraction, dimensionality reduction, clustering, classification, indexing, as well as the similarity metrics for images, and biomarkers. Furthermore, image analysis techniques for Regions Of Interest (ROIs) will include image segmentation and registration (for follow up purposes), feature extraction from ROIs, classification, and analysis of morphological variability. The ADNI database will be extremely valuable in our research.|