Ongoing Investigations

ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.

Principal Investigator  
Principal Investigator's Name: Joanna Williams
Institution: University of Otago
Department: Anatomy
Country:
Proposed Analysis: ADNI Plasma Proteome dataset: 1. Using the ADNI Plasma Proteome dataset we propose to carryout Significance Analysis of Microarrays (SAM) and Predictive analysis of Microarrays (PAM)analyses to extract a subset of analytes which can distinguish the plasma profiles of Alzheimer's Disease effected participants, MCI from healthy controls. We will determine the strength of the predictive subset using a second (local) cohort of individuals. 2. Using the ADNI Plasma Proteome dataset we will test whether a subset of analytes identified from the literature are predictive of disease state. 3. Apply additional statistical tests to validate predictions as our study develops.
Additional Investigators  
Investigator's Name: Helen Tsui
Proposed Analysis: as above
  
Investigator's Name: Robert Knight
Proposed Analysis: as above