ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Blaise Frederick |
| Institution: | McLean Hospital/Harvard Medical School |
| Department: | Brain Imaging Center/Dept. of Psychiatry |
| Country: | |
| Proposed Analysis: | My colleagues and I have been developing a multimodal (fMRI/NIRS) imaging method to perform detailed blood flow/perfusion imaging, and have developed a recent modification of this technique which allows for the extraction of perfusion information from resting state fMRI data alone, requiring no radionuclides or contrast agents (I can provide references to publications describing aspects of this technique). My hypothesis is that the this technique will be able to quantify the regional perfusion deficits characteristic of AD, which could aid in differential diagnosis of dementias. I would like to test the technique on a dataset containing subjects with PRAD subjects, matched controls, and subjects with other dementias, if available. I would require resting state MR, anatomical images, and some limited demographic data including diagnosis. |
| Additional Investigators | |
| Investigator's Name: | Lisa Nickerson |
| Proposed Analysis: | Dr. Nickerson will assist with the statistical analysis of the perfusion mapping. |
| Investigator's Name: | Yunjie Tong |
| Proposed Analysis: | Dr. Tong will assist with the perfusion modeling. |