ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
|Principal Investigator's Name:||Courtney Sutphen|
|Institution:||Washington University in Saint Louis|
|Proposed Analysis:||I am a first year graduate student at Washington University currently participating in rotations. During my rotations, I have worked with the Washington University Adult Children Study data set in order to find trends in cognitive decline between participants with and without a parental history of Alzheimer's Disease. I am currently working on analyzing the longitudinal MRI data from the same group using Freesurfer. I would like access to the ADNI data set so I may repeat these same analyses on ADNI data from multiple institutions. In order to accomplish this, I will analyze ADNI data using Freesurfer analysis on T1-weighted MRI images that have had two or more MRI scans. All images that are downloaded will run using Freesurfer and quality controlled to ensure adequate parcellation. For this analysis I will compare the rate of change in cognitively normal individuals who subsequently progressed to cognitively normal individuals who have remained stable. If possible I will also look at the effects of family history in this cohort.|