Ongoing Investigations

ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.

Principal Investigator  
Principal Investigator's Name: Andrew Saykin
Institution: Indiana University School of Medicine
Department: Radiology/Center for Neuroimaging
Country: United States of America
Proposed Analysis: Our team will begin data preparation for extracting planned and novel MRI and PET endophenotypes for use in whole genome association analyses after the genetic data become available. In addition to planned analyses (e.g., hippocampal atrophy) we plan to employ pattern recognition tools to extract novel phenotypic information. Further details are available upon request and we welcome collaborative projects with other groups.
Additional Investigators  
Investigator's Name: Li Shen
Proposed Analysis: Our team will begin data preparation for extracting planned and novel MRI and PET endophenotypes for use in whole genome association analyses after the genetic data become available. In addition to planned analyses (e.g., hippocampal atrophy) we plan to employ pattern recognition tools to extract novel phenotypic information. Further details are available upon request and we welcome collaborative projects with other groups.
  
Investigator's Name: John West
Proposed Analysis: Our team will begin data preparation for extracting planned and novel MRI and PET endophenotypes for use in whole genome association analyses after the genetic data become available. In addition to planned analyses (e.g., hippocampal atrophy) we plan to employ pattern recognition tools to extract novel phenotypic information. Further details are available upon request and we welcome collaborative projects with other groups.
  
Investigator's Name: Shannon Risacher
Proposed Analysis: Our team will begin data preparation for extracting planned and novel MRI and PET endophenotypes for use in whole genome association analyses after the genetic data become available. In addition to planned analyses (e.g., hippocampal atrophy) we plan to employ pattern recognition tools to extract novel phenotypic information. Further details are available upon request and we welcome collaborative projects with other groups.
  
Investigator's Name: Sungeun Kim
Proposed Analysis: Genome wide and candidate gene analyses of imaging data.
  
Investigator's Name: Shanker Swaminathan
Proposed Analysis: PhD Student, Medical and Molecular Genetics at Indiana University; new addition to ADNI Genetics Core team.
  
Investigator's Name: Vijay Ramanan
Proposed Analysis: Over the past year, the ADNI Genetics Core has continued to perform collaborative analyses (candidate gene, pathway, GWAS and CNV) leading to recent and pending publications and presentations (submitted to the ADNI DPC). Phenotypes have included structural MRI, FDG and amyloid PET, CSF and plasma biomarkers as well as cognition and clinical status. The core has also worked with the NIA Genetics Consortium (ADGC) to perform large scale meta-analyses across cohorts leading to several reports, as well as with the ADDNeuroMed consortium on a combined analysis.
  
Investigator's Name: Susan Conroy
Proposed Analysis: Over the past year, the ADNI Genetics Core has continued to perform collaborative analyses (candidate gene, pathway, GWAS and CNV) leading to recent and pending publications and presentations (submitted to the ADNI DPC). Phenotypes have included structural MRI, FDG and amyloid PET, CSF and plasma biomarkers as well as cognition and clinical status. The core has also worked with the NIA Genetics Consortium (ADGC) to perform large scale meta-analyses across cohorts leading to several reports, as well as with the ADDNeuroMed consortium on a combined analysis.
  
Investigator's Name: Kwangsik Nho
Proposed Analysis: Over the past year, the ADNI Genetics Core has continued to perform collaborative analyses (candidate gene, pathway, GWAS and CNV) leading to recent and pending publications and presentations (submitted to the ADNI DPC). Phenotypes have included structural MRI, FDG and amyloid PET, CSF and plasma biomarkers as well as cognition and clinical status. The core has also worked with the NIA Genetics Consortium (ADGC) to perform large scale meta-analyses across cohorts leading to several reports, as well as with the ADDNeuroMed consortium on a combined analysis.