ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Tejas Sankar |
| Institution: | University of Toronto |
| Department: | Neurosurgery |
| Country: | |
| Proposed Analysis: | We have recently demonstrated that deep brain stimulation of the fornix may be efficacious against the progression of Alzheimer's Disease. Consequently, we are interested in forniceal volume as a biomarker of disease progression in AD. We plan to perform manual volumetric segmentation of the fornix in a cohort of patients with AD at two time points, in order to determine its rate of atrophy over time in this patient population. We will also be testing a fully automated segmentation protocol and comparing it with our manual segmentation data. These analyses will prove valuable in ultimately assessing the suitability of candidates for, and the response of patients treated with, DBS for AD in future trials. |
| Additional Investigators | |
| Investigator's Name: | Andres Lozano |
| Proposed Analysis: | I serve as Dr. Sankar's (the principal investigator) supervisor in his current role as research fellow in stereotactic and functional neurosurgery; I will be playing a supervisory role in the study that Dr. Sankar has proposed above. |