ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
|Principal Investigator's Name:||Michael Miller|
|Institution:||Private biostatistical consultant: mfmillstat, Ltd.|
|Proposed Analysis:||I am investigating the impact of certain biomarkers (CSF, mri, PET) on outcomes as measured by the increase in CDR-SOB, or ADAS-Cog, to discriminate normals, MCI, and early Alzheimer's subjects. As a biostatistical consultant for Pfizer I studied a-beta142 and ptau (U Penn. 10/24/2010 version) and graphically depicted some interesting associations amongst the biomarker and clincial scales. I would like to continue with a later more complete version of the CSF data and expand into the other biomarker data, particularly hippocampal volume atrophy and any association with CDR-SOB and ADAS-Cog. My methodology involves multivariate kernel smoothing for graphical presentation using R. This work would be done for publication only, not to be "sold" to another 3rd party, and I would be happy to share and collaborate.|