ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Boubakeur BELAROUSSI |
| Institution: | BIOCLINICA |
| Department: | BioImaging Technologies |
| Country: | |
| Proposed Analysis: | One major challenge in understanding Central Nervous System (CNS) diseases is the identification of disease biomarkers to improve early diagnosis of neurodegenerative disease or to monitor treatment efficiency. The development of sophisticated brain MRI / PET techniques has allowed many neuroimaging studies to focus either on regional brain anatomical differences between healthy control and diseased subjects (cross-sectional studies) or regional anatomical differences over time for a given subject (longitudinal studies) in order to identify disease biomarkers. Our research work will focus in the development of new image processing techniques to: - Detect brain structures (hippocampus, amygdala, enthorinal cortex …) at baseline/screening using atlas-based segmentation techniques, - Track global and regional brain changes in specific subject populations (AD, MCI, Control …), using registration-based techniques, - Fuse information from different imaging modalities (MRI, PET …), - Correlate imaging data with clinical data. In order to perform such research work and to clinically validate the proposed techniques, we would like to get access to worldly recognized public databases such as yours. The proposed work will rigorously adhere to ADNI policies. I will be the main PI in charge of this research work. Best regards, Boubakeur BELAROUSSI |
| Additional Investigators | |
| Investigator's Name: | Joel Schaerer |
| Proposed Analysis: | Dr. Joel Schaerer will work with me on the current project and will more focus on hippocampal atrophy measurement. Best regards, Boubakeur BELAROUSSI |
| Investigator's Name: | Florent Roche |
| Proposed Analysis: | Florent Roche will be in support of the MRI part of the project. He will work on atlas-based segmentation and 3D intracranial cavity detection. |