ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
|Principal Investigator's Name:||Joihn Breitner|
|Institution:||McGill University Faculty of Medicine|
|Proposed Analysis:||Request A-beta 42 and t-tau concentrations from CSF of "CN" participants at baseline and at 1-yr follow-up as reported in P. Vemuri et al., Neuroogy 2010;75:143. Will use data to examine test-retest reliability of these measures within subjects (I presume we do not have samples drawn at closer intervals of time). This info will then be used to estimate sample sizes required for pilot biomarker-endpoint trials of interventions for possible mitigation of AD pathogenesis in pre-symptomatic phase of disease.|