ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
| Principal Investigator | |
| Principal Investigator's Name: | Markus Britschgi |
| Institution: | Roche |
| Department: | CNS Discovery |
| Country: | |
| Proposed Analysis: | I am collaborating with Tony Wyss-Coray at Stanford to identify molecular biomarkers in Alzheimer's disease (AD), a project that we started when I was working in his lab as postdoc and instructor. We would like to use bioinformatics tools to model pathological markers of AD including imaging data and CSF Abeta and tau based on the levels of expression of biomarkers in plasma. These biomarkers include cytokines, growth factors and other soluble proteins measured with luminex bead assays. We plan to validate proteins that best model the pathological markers in disease prediction models on the ADNI cohort as well as in independent data sets. |
| Additional Investigators | |
| Investigator's Name: | Tony Wyss-Coray |
| Proposed Analysis: | We would like to use bioinformatics tools to model pathological markers of AD including imaging data and CSF Abeta and tau based on the levels of expression of biomarkers in plasma. These biomarkers include cytokines, growth factors and other soluble proteins measured with luminex bead assays. We plan to validate proteins that best model the pathological markers in disease prediction models on the ADNI cohort as well as in independent data sets. |
| Investigator's Name: | Benoit Lehallier |
| Proposed Analysis: | biostatistics, bioinformatics, modeling |