ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
|Principal Investigator's Name:||Richard Sherva|
|Proposed Analysis:||The analysis will be centered around a recently discovered genetic polymorphism in TOMM40, a gene near APOE implicated in Alzheimer's disease pathogenesis. The goals are to determine the correlation structure among APOE and TOMM40 alleles, test for associations between these alleles or combinations thereof and Alzheimer's, as well as with potential endophenotypes measured through neuroimaging.|