Ongoing Investigations

ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.

Principal Investigator  
Principal Investigator's Name: John Kauwe
Institution: Brigham Young University
Department: Biology
Country:
Proposed Analysis: Aim 1: To measure mitochondrial genome copy number (mtGCN) in the ADNI samples. Aim 2: To examine the associations between mtGCN and Alzheimer’s disease in the ADNI samples. Aim 3: To examine the associations between select genetic variants in the mitochondrial and nuclear genome and mtGCN. ADNI phenotype data will be required to explore the mtGCN phenotype and its relationship to AD, imaging data and CSF biomarkers.
Additional Investigators  
Investigator's Name: Richard Cawthon
Proposed Analysis: Analysis of mtGCN phenotype for association with AD, imaging data and CSF biomarkers.
  
Investigator's Name: Carlos Cruchaga
Proposed Analysis: Assistance in Genetic Analysis
  
Investigator's Name: Taylor Maxwell
Proposed Analysis: Analysis of association between genetic markers and RBM phenotypes.