ADNI data is made available to researchers around the world. As such, there are many active research projects accessing and applying the shared ADNI data. To further encourage Alzheimer’s disease research collaboration, and to help prevent duplicate efforts, the list below shows the specific research focus of the active ADNI investigations. This information is requested annually as a requirement for data access.
|Principal Investigator's Name:||Igor Korolev|
|Institution:||Michigan State University|
|Department:||Neuroscience PhD Program|
|Proposed Analysis:||I am a graduate student working with Dr. Andrea Bozoki (Assistant Professor in Neurology and a neurologist with fellowship training in Cognitive and Geriatric Neurology). For my PhD thesis, I propose to validate MCI as a clinical entity by identifying associated structural and functional brain changes. This will be achieved by conducting whole-brain (voxel-based) analysis of MRI and PET data that compares normal and MCI subjects. This cross-sectional approach will be complemented by a longitudinal analysis of serial MRI and PET scans of normal subjects who subsequently develop MCI. Finally, baseline MRI and PET scans of normal subjects will be analyzed to identify potential imaging biomarkers that predict future development of MCI. Finally, genetic, neuropsychological, and molecular (CSF and blood) data will be correlated with imaging data.|